CircO2 Ingredients

Inside the CircO2 Formula

CircO2 brings together five ingredients selected for their role in supporting nitric oxide production and healthy circulation, delivered in a quick-dissolve tablet. No proprietary blends, no unlisted extracts — just a formula built around one connected wellness pathway.

Two boxes of CircO2 daily oxygen booster and circulation support

CircO2 Supplement Ingredients

The Complete CircO2 Formula

B
Supports the raw material the body uses for nitric oxide conversion.

Beetroot Powder

Beetroot is one of nature's richest sources of dietary nitrates. Once consumed, these nitrates can be converted into nitric oxide within the body, making beetroot a foundational ingredient in nitric-oxide-focused formulas.

  • Supports nitric oxide production
  • Promotes healthy blood flow
  • Supports endurance and stamina
  • Helps improve oxygen utilization
  • Encourages cardiovascular health

Beetroot has become a favorite among athletes and health-conscious individuals seeking natural circulation support.

LC
Supports the amino-acid pathway that feeds nitric oxide synthesis.

L-Citrulline

L-Citrulline is an amino acid that plays a direct role in nitric oxide production. It helps increase levels of L-arginine, which the body uses to produce nitric oxide.

  • Supports healthy circulation
  • Encourages nitric oxide synthesis
  • Supports exercise performance
  • Helps support endurance
  • Promotes cardiovascular wellness

Many experts consider L-Citrulline one of the most researched ingredients for naturally supporting nitric oxide levels.

H
A traditional botanical included for broader cardiovascular support.

Hawthorn

Hawthorn has been used for centuries to support cardiovascular health. It contains antioxidants and plant compounds that help support blood vessels and healthy circulation.

  • Supports heart health
  • Helps support blood vessels
  • Supports healthy blood pressure
  • Provides antioxidant protection
  • Encourages healthy circulation

Hawthorn remains one of the most widely used herbs for traditional cardiovascular support.

B12
Supports the energy and oxygen-transport side of circulation.

Vitamin B12

Vitamin B12 is essential for energy production, nervous system function, and red blood cell formation — all of which connect back to how efficiently the body delivers oxygen.

  • Supports healthy energy levels
  • Helps reduce fatigue
  • Supports brain function
  • Promotes nervous system health
  • Supports oxygen transport

Many adults do not obtain enough Vitamin B12 through diet alone, making supplementation a useful addition.

C
Provides antioxidant protection for the vascular system.

Vitamin C

Vitamin C is a powerful antioxidant that supports immune function and vascular health, and also helps protect the endothelial cells that line blood vessels.

  • Supports nitric oxide production
  • Protects blood vessels from oxidative stress
  • Supports immune health
  • Promotes healthy circulation
  • Encourages overall wellness

Vitamin C also helps maintain the health of endothelial cells that line blood vessels.

A Note on Evidence

Ingredient-Level Research vs. the Complete Formula

The ingredients above are widely discussed in the context of nitric oxide and circulation support. It's important to distinguish general, ingredient-level information from evidence about the complete CircO2 formula specifically — individual ingredient research doesn't automatically apply to any particular finished product.

CircO2 does not use proprietary blends, undisclosed extraction ratios, or unlisted standardization percentages. Always follow the exact ingredient and dosage information printed on the product label.

CircO2® is manufactured by Advanced Bionutritionals. This page is an independent summary and is not the official ingredient statement — always refer to the current product label for exact amounts.

Transparency First

No hidden ingredients. No unsupported clinical claims for the full formula. Just five ingredients, clearly listed, each with a defined role.

Keep Reading

Go Deeper on the Science

Dietary Supplement Disclaimer: CircO2 is a dietary supplement intended to support healthy circulation, nitric oxide production, energy, stamina, and everyday wellness. It is not intended to diagnose, treat, cure, or prevent any disease or medical condition.

Individual experiences may vary. Consult a qualified healthcare professional before using dietary supplements, particularly if you are pregnant, nursing, taking medication, or have a medical condition. These statements have not been evaluated by the Food and Drug Administration.

Independent Resource & Trademark Notice: This site is an independent educational and informational resource about CircO2 and is not the official website of, and is not operated, endorsed, or sponsored by, Advanced Bionutritionals. CircO2® and related product imagery are trademarks of Advanced Bionutritionals. For official product details, current pricing, and purchases, visit the manufacturer directly.

Ingredient ResearchHome / Formula & Ingredients / Beetroot and Nitric Oxide >Beetroot and Nitric Oxide: How Dietary Nitrates Support CirculationIngredient ResearchHome / Formula & Ingredients / L-Citrulline and Circulation >L-Citrulline and Circulation: Understanding Nitric Oxide SupportIngredient ResearchHome / Formula & Ingredients / Nitric Oxide and Healthy Blood Flow >Nitric Oxide and Healthy Blood Flow: Understanding Circulation and Daily WellnessIngredient ResearchHome / Formula & Ingredients / How to Choose a Nitric Oxide Supplement >How to Choose a Nitric Oxide Supplement: A Practical GuideSection OverviewReviews & Verdict